FIG.1.

Cluster map of aerolysin homologues. Protein sequences corresponding to aerolysin domains were clustered based on their pairwise similarity using the CLANS program. The clans containing sequences from more than one kingdom of life are indicated by black circles. Clans containing members of the PFAM aerolysin seed alignment are indicated by dashed circles. Bacteria appear in blue, plants in green, fungi in brown, and animals in red. GenInfo Identifier (GI) numbers of proteins appear in supplementary table 1 (Supplementary Material online).