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. 2012 Mar 15;5(5):627–635. doi: 10.1242/dmm.009407

Fig. 1.

Fig. 1.

Differing propensity towards HFD-induced body weight gain. (A) Phenotypic appearance of chow-fed Wistar rats compared with HFD-fed and partially DIO resistant (DIOres) or DIO sensitive (DIOsens) rats (Perez-Tilve et al., 2010). (B,C) Body weights (B) and epididymal, retroperitoneal and inguinal fat pad weights (C) after 11 months of exposure to chow or HFD (DIOres, DIOsens). (D) Changes in adipocytokine expression in retroperitoneal fat from chow-fed, DIOres and DIOsens rats after 11 months of diet exposure. Values are given as mean ± s.e.m. Significant differences were analyzed by one-way ANOVA and Bonferroni multiple comparison post tests and indicated as *P<0.05, **P<0.01 and ***P<0.001 vs chow-fed controls.