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. 2012 May 8;40(15):7162–7175. doi: 10.1093/nar/gks342

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© The Author(s) 2012. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Microarray analysis of RNA from purified control and Brdt^ΔBD1/ΔBD1 mutant round spermatids reveals genes that are both up-regulated and down-regulated in the mutant cells. (A) Heat map of the eight microarrays showing two groups of genes, one up-regulated and one down-regulated in mutant round spermatids. (B) A total of 415 genes exhibited statistically significant (adjPval ≤0.05) altered expression (logFC ≥1 or ≤−1) in mutant round spermatids. When the criteria were relaxed to include all differential expression, 1478 genes with altered expression were observed.