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. 2012 May 24;40(15):7452–7464. doi: 10.1093/nar/gks430

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© The Author(s) 2012. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Apparent rate constants for bimolecular synapsis, , (upper panel) and synaptic-complex dissociation, (lower panel) as functions of loxP concentration. Each data point is the average of at least three independent measurements and the error bars indicate the standard error. The horizontal line in the upper panel gives the overall average of for all values of [loxP] studied; the curve in the lower panel is the fit of an exponential function to the data for . Dashed curves are extrapolations of the [loxP] dependence to zero substrate concentration. The value of at [loxP] = 1 nM is 0.69 min⁻¹ and is indicated by the red filled triangle; this is the value of the rate constant used to calculate J under the conditions of intramolecular recombination.

Inline graphic — Apparent rate constants for bimolecular synapsis, , (upper panel) and synaptic-complex dissociation, (lower panel) as functions of loxP concentration. Each data point is the average of at least three independent measurements and the error bars indicate the standard error. The horizontal line in the upper panel gives the overall average of for all values of [loxP] studied; the curve in the lower panel is the fit of an exponential function to the data for . Dashed curves are extrapolations of the [loxP] dependence to zero substrate concentration. The value of at [loxP] = 1 nM is 0.69 min⁻¹ and is indicated by the red filled triangle; this is the value of the rate constant used to calculate J under the conditions of intramolecular recombination.