Table 3.
Patient | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
---|---|---|---|---|---|---|---|---|
Regimen | D + C | D + carbo | P + carbo | P + carbo | P + carbo | DCF | DCF | D + C |
Time for complete resolution of stridor (in hours) | 24 | 24 | 48 | 48 | 24 | 24 | 24 | 24 |
Number of cycles | 3 | 2 | 1 | 2 | 2 | 1 | 3 | 2 |
Response | SD | PR | PR | SD | PR | Not assessed | PR | PR |
Grade 3-4 haematological toxicity | Nil | Yes | Nil | Nil | Nil | Nil | Yes | Yes |
Grade 3-4 Gastrointestinal toxicity | Yes | Nil | Nil | Nil | Nil | Nil | Yes | Nil |
% reduction in tumor size | 10 | 47 | 37 | 20 | 40 | Not assessed | 80 | 37 |
Local Rx subsequently offered | CRT | CRT | RT | CRT | CRT | Defaulted | CRT | CRT |
D: docetaxel, C: cisplatin, Pacli: paclitaxel, Carb: carboplatin, F: 5FU, CR: complete response, PR: partial response, SD: stable response, CRT: chemoradiation and RT: radical radiation.