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Kaplan-Meier method was used to analyse survival of animals in the different experimental groups. Mortality rate was 50% after 2 h and 100% after 6 h LPS (n = 6) had been applied. All animals survived 2 h and 50% survived 6 h in the rolipram and 66% in the roflumilast group (n = 6). All control animals survived (n = 5).
