Figure 1. Oxyhaemoglobin saturation (via pulse oximetery) prior to (−15 min) and during (0–180 min) normoxia ( = 0.21) and hypoxia ( = 0.11), with and without sympathetic inhibition (48 h transdermal clonidine), during measurement of insulin sensitivity via the hyperinsulinaemic euglycaemic clamp.

Hypoxic gas breathing appreciably decreased oxyhaemoglobin saturation (P < 0.01) compared with normoxia. Oxyhaemoglobin saturation was unaffected by clonidine (P > 0.25). Data are means ± SEM.