Table 3.

Relationship of Scar Morphology Variables With Time to Event

Parameter	Death or ICD discharge		SCD or ICD discharge		Death
	Univariable		Univariable		Univariable
	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
Any scar	6.15 (1.48-25.53)	0.01	4.50 (1.07-18.89)	0.04	NA#	NA#
CAD type*	5.69 (1.33-24.39)	0.02	4.02 (0.91-17.76)	0.07	NA#	NA#
Non-CAD type†	4.71 (1.02-21.82)	0.05	3.23 (0.65-16.02)	0.15	NA#	NA#
Scar size (% of LV mass)	1.04 (1.01-1.07)	0.01	1.04 (1.00-1.07)	0.03	1.03 (0.99-1.08)	0.2
Scar size >5%	5.18 (2.02-13.25)	0.0006	4.76 (1.66-13.69)	0.004	5.89 (1.36-25.48)	0.02
Scar surface area (cm2)	1.005 (1.001-1.008)	0.008	1.005 (1.001-1.009)	0.03	1.006 (1.001-1.011)	0.03
Number of separate scars	2.07 (1.46-2.94)	<0.0001	1.91 (1.28-2.87)	0.002	3.11 (1.83-5.28)	<0.0001
Largest separate scar size (% of LV mass)	1.03 (1.00-1.06)	0.09	1.03 (1.00-1.07)	0.08	1.01 (0.96-1.06)	0.7
Largest separate surface area (cm2)	1.004 (1.000-1.008)	0.06	1.005 (1.000-1.009)	0.06	1.003 (0.997-1.009)	0.4
Segments with transmural scar (>75%)	1.06 (0.85-1.32)	0.6	1.11 (0.87-1.41)	0.4	0.80 (0.51-1.26)	0.3
Segments with transmural scar (>50%)	1.07 (0.93-1.25)	0.4	1.10 (0.93-1.29)	0.3	0.90 (0.69-1.17)	0.4
Segments with non-transmural scar (1-50%)	1.13 (1.04-1.22)	0.005	1.10 (1.00-1.22)	0.05	1.18 (1.05-1.32)	0.007
Segments with non-transmural scar (26-75%)	1.17 (1.04-1.31)	0.01	1.17 (1.02-1.34)	0.02	1.07 (0.89-1.29)	0.5
Grey zone (% of LV mass)	1.011 (0.994-1.027)	0.20	1.003 (0.980-1.026)	0.81	1.019 (1.000-1.039)	0.052

^*CAD-type scar required involvement of the subendocardium. Hazard ratios were calculated excluding patients with non-CAD type scar.

^†Isolated midwall or epicardial scar was considered Non-CAD type. Hazard ratios were calculated excluding patients with CAD type scar.

^#Not available because all patients who died had scar tissue.