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Antigen recognition by Langerhans cells present in the epithelium and initiation of T-cell response. (Abbreviations; PAMPs – Pathogen-associated molecular patterns, MHC – Major histocompatibility antigen, IL – Interleukin, TNF – Tumor necrosis factor, TGF – Transforming growth factor, GM-CSF – Granulocyte monocyte colony stimulating factor, TCR – T cell receptor)
