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. 2012 Feb 1;21(13):2343–2349. doi: 10.1089/scd.2011.0730

FIG. 1.

FIG. 1.

Expression of LIN28 and LIN28B during human fetal ovarian development. Quantitative reverse transcription-polymerase chain reaction (qRT-PCR) analysis reveals expression of LIN28 (A) to be highest at 8–11 wga, and significantly lower at 14–16 wga and 17–20 wga, coincident with the onset of germ cell differentiation [***P<0.001 vs. 8–11 wga (ANOVA with Neumann-Keuls post hoc testing), n=6–8 ovaries per gestational group]. LIN28B expression (B) remained unchanged across gestation. Values denote mean±SEM. ANOVA, analysis of variance; SEM, standard error of the mean.