Figure 4.

Comparison of vapor nanobubbles incidence and size. Vapor nanobubbles were generated from individual and combined treatments with MUC1-targeted (214D4) and EGFR-targeted (C225) AuNPs in both MUC1 and EGFR positive HES cells (blue) and MUC1 negative, EGFR positive HS-5 cells (tan). Cells were incubated with AuNPs for 1 hour, and then individual cells were irradiated with a single laser pulse (532 nm, 500 ps, 72 mJ/cm²). A) The probability of producing a bubble in a cell following irradiation. B) The size of the transient vapor nanobubbles is proportional to their lifetimes. Error bars represent mean +/- SD.