Table 1.
Clinical characteristics of the study population.
| Characteristics | Group (a) (n=9) | Group (b) (n=40) | Group (c) (n=50) | P value |
|---|---|---|---|---|
| Male gender, n (%) | 8 (88.9) | 37 (94.9) | 46 (92) | 0.78 |
| Age (years) | 55.4±4.3 | 53.8±3.2 | 54.2±3.8 | 0.82 |
| Body mass index (kg/m2) | 25±5 | 26±6 | 26±5 | 0.87 |
| Hypertension n (%) | 3 (33.3) | 15 (38.5) | 18 (36) | 0.95 |
| Hyperlipidemia n (%) | 3 (33.3) | 11 (28.2) | 15 (30) | 0.95 |
| Diabetes mellitus n (%) | 2 (22.2) | 10 (25.6) | 13 (26) | 0.97 |
| Current smoker n (%) | 6 (66.7) | 28 (71.8) | 34 (68) | 0.91 |
| UN(mmol/L) | 4.1±0.4 | 4.2±0.5 | 4.6±0.3 | 0.72 |
| Cr(μmol/L) | 55.3±4.7 | 56.9±4.1 | 57.8±3.6 | 0.83 |
| Cardiovascular history n (%) | ||||
| Previous MI/ACS | 6 | 25 | 33 | 0.98 |
| Previous PCI | 5 | 20 | 26 | 0.97 |
| Medication | ||||
| Aspirin(%) | 8 (88.9) | 34 (87.1) | 43 (86) | 0.97 |
| clopidogrel(%) | 6 (66.7) | 27 (69.2) | 37 (74) | 0.84 |
| ACEI/ARB(%) | 7 (77.8) | 30 (76.9) | 41 (82) | 0.83 |
| β-blocher(%) | 6 (66.7) | 28 (71.8) | 37 (74) | 0.90 |
| Statin(%) | 7 (77.8) | 33 (84.6) | 43 (86) | 0.82 |
| Computed tomography coronary angiography | ||||
| Length of the occlusion (mm) | 0.8±0.5 | 1.1±0.6 | 1.7±0.8 | <0.001 |
| Severe calcification present | 0 (0) | 3 (7.5) | 5 (10) | <0.001 |
| Length of calcification (mm) | 0 | 1.2±0.5 | 1.1±0.6 | <0.001 |
| Collateralization present | 7 (77.8) | 33 (82.5) | 37 (74) | 0.628 |
Values are presented as mean ± SEM or number or proportion.