Table 8.
ROC analysis of measured parameters in the PA-treated group of rats
| Parameter | Area under the curve | Cutoff value | Sensitivity % | Specificity % |
|---|---|---|---|---|
| GSH (μg/ml) |
0.844 |
70.12 |
100.0% |
25.0% |
| GPX (U/100 mg) |
1.000 |
6.03 |
100.0% |
20.0% |
| MD |
0.984 |
0.09 |
87.5% |
87.5% |
| Vitamin C levels in brain |
0.944 |
24.23 |
100.0% |
16.7% |
| Catalase |
0.688 |
5.36 |
85.7% |
12.5% |
| CK (U/L) |
1.000 |
79.32 |
100.0% |
80.0% |
| LDH (umoles/L) |
0.944 |
2431.78 |
100.0% |
16.7% |
| Acetic acid |
1.000 |
0.02 |
100.0% |
40.0% |
| PA |
1.000 |
0.02 |
100.0% |
80.0% |
| 18:2-n6 (Linoleic) |
0.959 |
2.92 |
100.0% |
14.3% |
| 18:3-n6 (γ -linolenic) |
0.847 |
1.51 |
100.0% |
14.3% |
| AA |
1.000 |
0.64 |
100.0% |
14.3% |
| EPA |
1.000 |
0.665 |
100.0% |
100% |
| 22:5-n3 Docosapentaenoic (clupanodonic) |
1.000 |
0.635 |
100.0% |
100% |
| 22:5-n6 Docosapentaenoic (Osbond) |
0.959 |
1.49 |
100.0% |
14.3% |
| DHA |
1.000 |
0.44 |
100.0% |
14.3% |
| PE |
1.000 |
0.19 |
100.0% |
25.0% |
| PS |
1.000 |
0.34 |
100.0% |
25.0% |
| PC |
1.000 |
4.89 |
100.0% |
25.0% |
| Caspase3 |
1.000 |
125.45 |
100.0% |
75.0% |
| IL-6 |
0.917 |
136.48 |
66.7% |
75.0% |
| TNFα |
1.000 |
125.03 |
100.0% |
100.0% |
| INFγ |
1.000 |
95.15 |
100.0% |
80.0% |
| HSP70 |
1.000 |
35.19 |
100.0% |
80.0% |
| GABA |
1.000 |
93.025 |
100.0% |
100.0% |
| Serotonin |
0.944 |
8.19 |
100.0% |
100% |
| Dopamine |
0.972 |
19.69 |
100.0% |
25.0% |
| Adrenaline |
1.000 |
6.65 |
100.0% |
33.3% |
| Noradrenaline |
1.000 |
5.13 |
100.0% |
33.3% |
| Tailed% |
1.000 |
4.70 |
100.0% |
66.7% |
| Tail length (μm) |
1.000 |
1.18 |
100.0% |
66.7% |
| Tail moment | 1.000 | 1.51 | 100.0% | 66.7% |
AA arachidonic acid; CK creatine kinase; DHA docosahexanoic acid; EPA eicosapentaenoic acid; GABA gamma aminobutyric acid; GPX glutathione peroxidase; GSH glutathione; LDH lactate dehydrogenase; MD malondialdehyde; PA propionic acid; PC phosphatidylcholine; PE phosphatidylethanolamine; PS phosphatidylserine; ROC receiver operating characteristics.