Table 1.
Group averaged data for glucose, lactate, pH, pC02 and hemoglobin
| |
Glucose (mg/dl) |
Lactate (mmol/l) |
pH |
|
p02(mmHg) |
pC02(mmHg) |
Hemoglobin (g/l) |
|||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Baseline | End | Baseline | End | Baseline | End | Baseline | End | Baseline | End | Baseline | End | |
| SHAM |
63 ± 8 |
84 ± 21 |
0.8 ± 0.05 |
0.9 ± 0.1 |
7.49 ± 0.06 |
7.47 ± 0.03 |
250 ± 18 |
246 ± 29 |
36 ± 3 |
38 ± 4 |
140 ± 10 |
120 ± 20** |
| VGX |
98 ± 30 |
98 ± 18 |
0.8 ± 0.03 |
0.9 ± 0.1 |
7.45 ± 0.05 |
7.50 ± 0.06 |
265 ± 19 |
250 ± 23 |
41 ± 8 |
33 ± 4 |
140 ± 10 |
130 ± 10* |
| VGX + STIM |
71 ± 15 |
105 ± 49 |
0.9 ± 0.2 |
1.3 ± 0.5 |
7.52 ± 0.06 |
7.51 ± 0.04 |
259 ± 19 |
248 ± 5 |
37 ± 5 |
36 ± 5 |
130 ± 10 |
100 ± 20* |
| SHAM LPS |
65 ± 13 |
69 ± 26 |
0.8 ± 0.1 |
1.9 ± 0.5s |
7.47 ± 0.05 |
7.45 ± 0.03 |
250 ± 14 |
233 ± 30 |
40 ± 4 |
35 ± 3* |
150 ± 10 |
120 ± 10 s |
| VGX LPS |
82 ± 22 |
129 ± 90 |
0.8 ± 0.1 |
2.2 ± 0.7s |
7.45 ± 0.07 |
7.37 ± 0.08** |
272 ± 13 |
249 ± 26 |
41 ± 6 |
39 ± 4 |
150 ± 10 |
120 ± 20** |
| VGX LPS+ STIM | 85 ± 25 | 65 ± 20 | 0.9 ± 0.1 | 1.8 ± 0.6*** | 7.48 ± 0.4 | 7.43 ± 0.1 | 251 ± 22 | 233 ± 21 | 38 ± 2 | 35 ± 5 | 130 ± 10 | 100 ± 20*** |
Data are given as the mean ± standard deviation (SD) together with statistical differences. Significance is given as: *, P < 0.05; **, P < 0.01; ***, P < 0.001; s, P < 0.0001 compared with baseline. LPS, lipopolysaccharide; pC02, partial pressure of carbon dioxide; SHAM, sham surgery; VGX, bilateral vagotomy; VGX + STIM, bilateral vagotomy and distal vagus nerve stimulation.