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. Author manuscript; available in PMC: 2013 Jan 23.
Published in final edited form as: Angew Chem Int Ed Engl. 2011 Dec 7;51(4):966–970. doi: 10.1002/anie.201107236

Figure 2.

Figure 2

Imaging of KIAA1363 activity in cancer cells treated with JW576. (a) Confocal imaging of JW576-treated PC3 cells. (b) Gel analysis of PC3 cells treated as in (a) with JW576 in the presence or absence of 10× JW480. (c) Confocal imaging of prostate (PC3), breast (231MFP) and ovarian (SKOV3) cancer cells treated with JW576 ± 10× JW480 competitor for 2 hr. (d) JW576 treatment of mock- or KIAA1363-transfected COS7 cells in the presence or absence of 10× JW480 for 2 hr. Arrows in (b) indicate labeled-KIAA1363. Scale bars = 5 μm.