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. 2012 Aug 17;61(9):2340–2348. doi: 10.2337/db12-0049

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© 2012 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 7. — Rapamycin/IL-2 combination therapy transiently augments NK cell frequency. Thawed PBMCs were stained for viability, CD56, CD3, and CD16. A: The number of CD56⁺CD3⁻ NK cells of PBMCs are shown for individual subjects. B: The average ± SD frequencies for CD56^hiCD16⁺ (open squares), CD56^hiCD16⁻ (closed triangles), and CD56^loCD16⁺ (closed circles) subsets of CD56⁺ NK cells within the live lymphocyte gate are shown. Statistical significance was determined by a one-way ANOVA, noted in the graph. Significance from time 0 to each time point was determined using a paired Student t test and is indicated with an asterisk. *P ≤ 0.05, **P ≤ 0.01.