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. 2012 Aug 22;7(8):e43645. doi: 10.1371/journal.pone.0043645

Figure 3. Inhibition of HDACs activity by MPT0E028 and SAHA.

Figure 3

(A) Inhibition of HDACs activity in HeLa nuclear extracts. Data were expressed as the mean of at least 3 independent experiments. (B) Inhibition of total HDAC activity by MPT0E028 and SAHA. HCT116 cells were treated with the indicated concentrations of MPT0E028 and SAHA for 24 h, and the nuclear proteins were isolated to determine the inhibition of total HDAC enzyme activity. Data are expressed as the mean±S.E.M. of at least 3 independent experiments.