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. 2012 Aug 22;7(8):e43320. doi: 10.1371/journal.pone.0043320

Figure 1. Skin application of imiquimod increases relative and absolute respiratory DC numbers.

Figure 1

Skin of mice was treated with TLR7 ligand imiquimod or placebo in a daily fashion and relative and absolute respiratory leukocyte subsets were quantitated by flow cytometry at the indicated time points (see gating stategy in Fig. S1). Total lung leukocytes (A), respiratory macrophages (B), respiratory granulocytes (C) and respiratory DC numbers after imiquimod exposure (D). Mean ± SEM; n ≥4; *p<0.05; **p<0.01; ***p<0.001 versus placebo.