Figure 2. Accumulation of respiratory DC after skin TLR7 triggering is caused by an increase of monocytic DC and CD11b^high DC subsets.

Modulation of respiratory DC subsets pDC, CD103⁺ DC, monocytic DC and CD11b^high DC (see gating strategy in Fig. S2) after skin imiquimod exposure versus placebo as described in materials and methods (A, B). Mean ± SEM; n ≥4; *p<0.05; **p<0.01; ***p<0.001 versus placebo.