Table 3. Previous CRYBA3/BA1 gene mutations associated with congenital cataracts.

Bp exchange	Aa exchange	Biologic consequence	Origin of family	Reference
c.215+1G>A	Splice site mutation	zonular lamellar opacities cataract and floriform	Indian	[6]
c.215+1G>C	Splice site mutation	pulverulent, star-shaped, shieldlike and radial cataract	Brazilian	[26]
c.215+1G>T	Splice site mutation	Y-suture, nucleus and cortical cataract	Chinese	[27]
c.215+1G>A	Splice site mutation	Y-sutural,mild nucleus and cortical dot cataract	Australian	[32]
c.215+1G>A	Splice site mutation	progressive childhood nucleus and peripheral cortex cataract	Chinese	[33]
c.215+1G>A	Splice site mutation	posterior polar cataract	Chinese	[34]
c.215+1G>A	Splice site mutation	zonular cataract with sutural opacity	Indian	[35]
c.279_281del	p.Gly91del	nuclear cataract	Chinese	[28]
c.279_281del	p.Gly91del	pulverulent nuclear congenital cataracts	Chinese	[29]
c.279_281del	p.Gly91del	pulverulent lamellar congenital cataracts	Chinese	[29]
c.279_281del	p.Gly91del	nuclear cataract	Swiss	[30]
c.279_281del	p.Gly91del	lamellar cataract	Britain	[31]