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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Neurogastroenterol Motil. 2012 Jul 26;24(9):e450–e459. doi: 10.1111/j.1365-2982.2012.01981.x

Figure 7.

Figure 7

Representative recordings of membrane potential and action potential bursting in smooth muscle cells from the distal colon of a WT mouse and the effects of the BK channel blocker, paxilline. Upper trace shows a slow time base recording of action potential bursting and membrane potential. Paxilline causes a membrane depolarization but action potential bursting persists. Lower traces show expanded views of action potential bursting in the absence (left) and presence (right) of paxilline. Paxilline caused a prolongation of the bursts of action potentials.