Observation 3, Alicia: a congenital bow of the tibia in NF1, b fracture at 3 years old, c, d first procedure (Masquelet’s) and application of rhBMP2, e 7 months follow-up, pseudarthrosis relapses, f second application of rhBMP2 and bone grafting, g pseudarthrosis relapses, h third procedure with intramedullary nailing (Fassier–Duval nail) and bone grafting (May 2008), i bone consolidation (October 2008), j, k result at final follow-up (May 2011)