Table 2.
Summary of the three cases reported in this study: three procedures used Masquelet’s procedure, five anatomic sites were treated with the application of human recombinant bone morphogenetic protein 2 (rhBMP2), and three anatomic sites healed
| Patients | Number of previous surgeries | Number of treated anatomic sites | Result of Masquelet’s procedure | Number of healed anatomic sites after rhBMP application | Surgical technique of rhBMP application | Follow-up (months)/complications | Delay for consolidation (weeks) |
|---|---|---|---|---|---|---|---|
| 1A | 1 (Masquelet’s procedure) | 1 | Healing proximally and pseudarthrosis distally Total bone rebuilding |
1 | Screwed plate and bone grafting | 12 (fracture) | 14 |
| 1B | 2 | 1 | – | 0 | Screwed plate and bone grafting | 9 (infection and resorption of bone graft) | – (amputation) |
| 2 | 2 (1 Masquelet’s procedure) | 1 | Healing proximally and pseudarthrosis distally Total bone rebuilding |
1 | Screwed plate and bone grafting | 65 | 28 |
| 3A | 0 | 1 (Masquelet’s procedure) | Healing distally and pseudarthrosis proximally Total bone rebuilding |
1 (1 extremity) | Bone grafting and cast immobilization | 4 (pseudarthrosis at 1 out of 2 extremities) | – (1 extremity: 12) |
| 3B | 1 | 1 | – | 0 | Screwed plate and bone grafting | 31 (fracture) | – (pseudarthrosis: nailing and bone grafting, healed 24 later) |
| Total/mean | 5 | Three bone rebuilding Three pseudarthrosis |
3 | 24 months | 18 weeks |