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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Curr Opin Cell Biol. 2012 Jun 8;24(4):541–546. doi: 10.1016/j.ceb.2012.05.005

Fig. 2. Asymmetric stem cell division and centrosome inheritance.

Fig. 2

A. Drosophila male germline stem cells (GSCs) inherit the mother centrosome upon division. The mother centrosome is anchored to the interface between the GSC and the hub cells. The hub secretes the signaling ligand (Unpaired, Upd) to specify GSC identity.

B. Mouse radial glial progenitor cells inherit the mother centrosome upon division. The mother centrosome is located near the basal membrane throughout the cell cycle, even during interkinetic nuclear migration. This mother centrosome is also involved in primary cilia formation of radial glial progenitor cells.

C. Drosophila neuroblasts inherit the daughter centrosome upon division. During each cell cycle, the mother centrosome is inactivated, while the daughter acquires robust microtubule organizing activity.