TABLE 1.
Ovarian weight and ovulation and fertilization rates in untreated and eCG/hCG-treated mice
| Parameter | Genotype |
||
|---|---|---|---|
| +/+ | +/− | −/− | |
| Ovarian weight (mg) | |||
| Untreated | 6.0 ± 0.7 (6) | ND | 5.3 ± 1.1 (6) |
| eCG/hCG-treated | 15.9 ± 1.2 (7) | 15.3 ± 0.5 (9) | 12.4 ± 0.7 (7)* |
| Ovulation rate | |||
| Untreated | 8.0 ± 0.6 (11) | ND | 6.0 ± 0.7 (9)* |
| eCG/hCG-treated | 21.1 ± 2.6 (9) | 23.6 ± 3.8 (8) | 9.6 ± 3.1 (8)* |
| Fertilization rate (%) | |||
| eCG/hCG-treated | 76 (95/125) (6) | 77.9 (141/181) (8) | 56.7 (34/60) (5)* |
Ovary pairs were weighed in untreated and eCG/hCG-treated mice. Number of oocytes released per ovulation is expressed as the ovulation rate in untreated mice. For eCG/hCG-treated mice, ovulation rate is the sum of 2-cell embryos and 1-cell, unfertilized oocytes. Fertilization rates in eCG/hCG-treated mice were statistically analyzed by χ2 test. Numbers in parentheses indicate numbers of mice. ND, not determined.
*
P < 0.05 vs. other genotypes in same row.