Table 4.

Descriptive statistics for PRO measures at screening and baseline (pooled dataset; N = 698)¹.

	N	Mean (SD)	Median	Range
NPRS pain now (screening)	698	4.7 (2.2)	5	0.0–10.0
NPRS average pain in last 24 hours2 (baseline)	695	5.8 (1.6)	6	1.6–9.9
BPI (screening)
Pain at its worst in the last 24 hours	698	6.8 (2.0)	7	0.0–10.0
Pain at its least in the last 24 hours	698	3.1 (2.1)	3	0.0–10.0
Pain on average in the last 24 hours	698	5.1 (1.7)	5	0.0–10.0
Pain right now	698	4.5 (2.3)	4	0.0–10.0
BPI pain interference scores (screening)
A. General activity	698	3.6 (2.9)	3	0.0–10.0
B. Mood	697	3.7 (2.8)	3	0.0–10.0
C. Walking ability	697	2.5 (2.9)	1	0.0–10.0
D. Normal work	697	3.6 (2.9)	3	0.0–10.0
E. Relation with other people	698	2.5 (2.6)	2	0.0–10.0
F. Sleep	698	4.1 (3.1)	4	0.0–10.0
G. Enjoyment of life	698	4.2 (2.9)	4	0.0–10.0
SF-MPQ (screening)
Present pain intensity	696	2.1 (0.9)	2	0.0–5.0
SF-36v2 (screening)
Physical functioning	698	59.5 (27.9)	60	0.0–100.0
Role-physical	698	55.6 (28.0)	56	0.0–100.0
Bodily pain	698	44.0 (18.9)	41	0.0–100.0
General health	698	67.4 (19.3)	67	5.0–100.0
Role-emotional	698	71.9 (27.3)	75	0.0–100.0
Vitality	698	52.0 (20.7)	56	0.0–100.0
Mental health	698	71.8 (18.7)	75	5.0–100.0
Social functioning	698	71.6 (26.2)	75	0.0–100.0
PGIC (Week 12)	697	0.9 (1.2)	1	−3.0–3.0
CGIC3 (Week 12)	349	1.0 (1.2)	1	−2.0–3.0

BPI: Brief Pain Inventory; CGIC: Clinician Global Impression of Change; NPRS: Numeric Pain Rating Scale; PGIC: Patient Global Impression of Change; SD: standard deviation.

¹Pooled dataset included data from two clinical trials, Studies C116 (N = 349) and C117 (N = 349).

²Average NPRS pain rating for 7 days prior to visit.

³Study C117 only.