Table 1.
Week | 1 | 2 | 3 | 11 | 12 |
---|---|---|---|---|---|
Controld | 100 ± 2.1 | 100 ± 3.7 | 100 ± 1.4 | 100 ± 4.9 | 100 ± 6.0 |
5 mg/kg allicine | 90.3 ± 2.7a | 88.1 ± 4.2 | 80.0 ± 2.3a | 70.7 ± 5.9a | 82.0 ± 4.7 |
10 mg/kg allicine | 54.3 ± 0.5b | 74.2 ± 11.7a | 68.9 ± 1.6b | 80.5 ± 3.1a | 80.1 ± 4.3 |
20 mg/kg allicine | 42.0 ± 1.3c | 65.5 ± 5.7b | 53.0 ± 3.3b | 65.4 ± 3.2b | 67.7 ± 2.4a |
Normal (regular diet)e | 89.9 ± 12.8a | 85.6 ± 2.6a | 82.3 ± 4.0a | 93.4 ± 14.8 | 82.7 ± 15.9 |
The data are mean ± S.D. and significantly different at a P < 0.05, b P < 0.01, and c P < 0.001 by the unpaired Student's t-test.
dThe high cholesterol control group, 200 μL PBS (pH 7.4) was served instead of allicin as a negative control.
eThe results are expressed as % of the high cholesterol control.