Table 2.
Serum parameters after 12-week allicin administration (n = 6, mM).
Parameter | 5 mg/kg | 10 mg/kg | 20 mg/kg | Controlc | Normal (regular diet) |
---|---|---|---|---|---|
High-cholesterol diet (allicin administered) | |||||
TC | 43.91 ± 4.21b | 32.91 ± 1.34b | 37.45 ± 0.80b | 57.82 ± 3.51b | 32.99 ± 0.55 |
TG | 1.66 ± 0.34a | 1.33 ± 0.11b | 1.89 ± 0.19b | 2.11 ± 0.35b | 1.04 ± 0.23 |
GLU | 8.73 ± 0.49 | 8.22 ± 1.52 | 8.10 ± 0.14 | 14.08 ± 3.16b | 8.38 ± 0.75 |
HDL-C | 1.25 ± 0.20a | 1.71 ± 0.59 | 1.60 ± 0.45 | 1.61 ± 0.16 | 1.94 ± 0.22 |
LDL-C | 1.06 ± 0.52a | 1.04 ± 0.22a | 0.80 ± 0.15a | 1.83 ± 0.50 | 1.57 ± 0.43 |
The data are mean ± S.D. and significantly different at a P < 0.05 and b P < 0.01 by the unpaired Student's t-test.
TC: total cholesterol, TG: triglyceride, GLU: plasma glucose, HDL-C: high-density lipoprotein cholesterol, LDL-C: low-density lipoprotein cholesterol.
cThe high cholesterol control group, 200 μL PBS (pH 7.4) was served instead of allicin as a negative control.