Table 2.

HRs for childhood cancer according to the Apgar score at 5 min

Apgar score	Cases (rate per 1000)	Crude HR	Adjusted HR (95% CI) †
0	3 (0.7)	0.47 (0.15 to 1.45)	0.56 (0.18 to 1.73)
1	15 (2.9)	2.44 (1.47 to 4.04)*	2.17 (1.31 to 3.60)*
2	6 (1.9)	1.89 (0.61 to 3.54)	1.72 (0.77 to 3.82)
3	9 (2.1)	1.85 (0.96 to 3.56)	1.67 (0.87 to 3.21)
4	14 (2.2)	1.61 (0.94 to 2.78)	1.48 (0.86 to 2.55)
5	21 (2.1)	1.40 (0.91 to 2.18)	1.32 (0.85 to 2.05)
0–5 combined	68 (2.0)	1.54 (1.21 to 1.96)*	1.46 (1.15 to 1.89)*
6	28 (1.5)	1.03 (0.71 to 1.49)	0.95 (0.66 to 1.38)
7	61 (1.6)	1.15 (0.99 to 1.34)	1.00 (0.77 to 1.29)
8	177 (1.7)	1.18 (1.08 to 1.29)	1.08 (0.93 to 1.26)
6–8 combined	266 (1.7)	1.12 (0.99 to 1.27)	1.05 (0.92 to 1.18)
9–10	7216 (1.6)	1.0 (ref)	1.0 (ref)

*p<0.05.

†Adjusted for country, sex, maternal factors at child birth (age, education and smoking during pregnancy) and birth characteristics of the child (birth weight, gestational age and birth order).