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. 2012 Aug 8;2(4):e001095. doi: 10.1136/bmjopen-2012-001095

Table 3.

HRs for childhood cancer according to the Apgar score at 5 min, by age at diagnosis

Age at diagnosis Apgar score Cases (rate, ‰) Crude HR (95% CI) Adjusted HR (95% CI)†
Under 6 months 0–5 20 (0.6) 6.65 (4.15 to 10.65)* 6.04 (3.73 to 9.76)*
6–8 39 (0.2) 2.43 (1.73 to 3.39)* 2.17 (1.54 to 3.05)*
9–10 465 (0.1) 1.0 (ref) 1.0 (ref)
6 months–5 years 0–5 25 (0.9) 1.21 (0.82 to 1.79) 1.18 (0.80 to 1.76)
6–8 134 (0.9) 1.15 (0.97 to 1.36) 1.09 (0.92 to 1.30)
9–10 3678 (0.8) 1.0 (ref) 1.0 (ref)
>5 years 0–5 23 (1.0) 1.17 (0.78 to 1.77) 1.10 (0.73 to 1.65)
6–8 93 (0.7) 0.89 (0.73 to 1.10) 0.83 (0.67 to 1.02)
9–10 3223 (0.8) 1.0 (ref) 1.0 (ref)

*p<0.05.

†Adjusted for country, sex, maternal factors at child birth (age, education and smoking during pregnancy) and birth characteristics of the child (birth weight, gestational age and birth order).