Table 3.

HRs for childhood cancer according to the Apgar score at 5 min, by age at diagnosis

Age at diagnosis	Apgar score	Cases (rate, ‰)	Crude HR (95% CI)	Adjusted HR (95% CI)†
Under 6 months	0–5	20 (0.6)	6.65 (4.15 to 10.65)*	6.04 (3.73 to 9.76)*
	6–8	39 (0.2)	2.43 (1.73 to 3.39)*	2.17 (1.54 to 3.05)*
	9–10	465 (0.1)	1.0 (ref)	1.0 (ref)
6 months–5 years	0–5	25 (0.9)	1.21 (0.82 to 1.79)	1.18 (0.80 to 1.76)
	6–8	134 (0.9)	1.15 (0.97 to 1.36)	1.09 (0.92 to 1.30)
	9–10	3678 (0.8)	1.0 (ref)	1.0 (ref)
>5 years	0–5	23 (1.0)	1.17 (0.78 to 1.77)	1.10 (0.73 to 1.65)
	6–8	93 (0.7)	0.89 (0.73 to 1.10)	0.83 (0.67 to 1.02)
	9–10	3223 (0.8)	1.0 (ref)	1.0 (ref)

*p<0.05.

†Adjusted for country, sex, maternal factors at child birth (age, education and smoking during pregnancy) and birth characteristics of the child (birth weight, gestational age and birth order).