Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2013 Jul 1.

Published in final edited form as: Xenotransplantation. 2012 Jul;19(4):233–243. doi: 10.1111/j.1399-3089.2012.00712.x

Platelet aggregation in 50% diluted blood was compared between humans, baboons, and monkeys. Collagen at 3 and 5 µg/mL (A) induced significantly greater platelet aggregation in humans than in baboons, and comparable aggregation in monkeys. With ristocetin at 0.5 or 1 mg/ml (B), no significant differences were found between species. Platelet activation with ADP at 20 and 40 µM (C) induced significantly greater platelet aggregation in humans and monkeys than in baboons. Platelet activation with thrombin at 1 and 5 IU/ml (D) induced significantly greater platelet aggregation in humans and monkeys than in baboons. Values of mean percentage (%) of aggregation are indicated in the figure. (*p<0.05, **p<0.01, ***p<0.001).

Platelet aggregation in 50% diluted blood was compared between humans, baboons, and monkeys. Collagen at 3 and 5 µg/mL (A) induced significantly greater platelet aggregation in humans than in baboons, and comparable aggregation in monkeys. With ristocetin at 0.5 or 1 mg/ml (B), no significant differences were found between species. Platelet activation with ADP at 20 and 40 µM (C) induced significantly greater platelet aggregation in humans and monkeys than in baboons. Platelet activation with thrombin at 1 and 5 IU/ml (D) induced significantly greater platelet aggregation in humans and monkeys than in baboons. Values of mean percentage (%) of aggregation are indicated in the figure. (*p<0.05, **p<0.01, ***p<0.001).