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. Author manuscript; available in PMC: 2012 Aug 23.
Published in final edited form as: Clin Cancer Res. 2008 Jun 1;14(11):3372–3379. doi: 10.1158/1078-0432.CCR-07-4433

Table 2.

Association between traditional clinical variables and APM/T-cell factors

Clinical variables Positive expression
TAP1 TAP2 Tapasin HLA-HC β2m IT CD3+/CD8+ T cells PT CD3+/CD8+ T cells
Age NS NS 0.035 NS NS NS NS
Low stage 0.008 NS 0.001 NS NS NS 0.001
Low grade 0.011 0.029 0.003 NS 0.035 NS NS
Serous histology NS NS NS NS NS NS NS
Preoperative CA125 NS NS NS NS NS NS 0.014
Ascites (−) NS NS NS NS NS NS NS
Optimal cytoreduction NS NS NS NS NS NS NS
Lymph nodes (−) 0.006 0.021 0.045 NS NS NS 0.018
Distant metastasis (−) NS NS NS NS 0.011 NS NS
Positive expression
 TAP1 ** <0.001 <0.001 NS <0.001 NS 0.018
 TAP2 <0.001 ** <0.001 <0.001 <0.001 0.003 0.001
 Tapasin <0.001 <0.001 ** 0.007 <0.001 0.007 NS
 HLA-HC NS <0.001 0.007 ** <0.001 0.005 <0.001
 β2m <0.001 <0.001 <0.001 <0.001 ** 0.001 0.011
 IT CD3+/CD8+ T cells NS 0.003 0.007 0.005 0.001 ** <0.001
 PT CD3+/CD8+ T cells 0.018 0.001 NS <0.001 0.011 <0.001 **

NOTE: χ2 Test was used for categorical data and the Wilcoxon rank sum test was used for continuous variables.

Abbreviations: NS, not significant; β2m, β2 microglobulin; IT, intratumoral; PT, peritumoral;

**

NA, not applicable.