Skip to main content
. Author manuscript; available in PMC: 2013 Aug 17.
Published in final edited form as: Circ Res. 2012 Jun 26;111(5):532–542. doi: 10.1161/CIRCRESAHA.112.270983

Figure 1. Myocardial ischemia/reperfusion (I/R) impairs proteasome peptidase activities in mouse hearts.

Figure 1

GFPdgn tg mice were subject to myocardial I/R created by ligation (30min) and subsequent release of the ligation (24h) of the anterior descending artery. Crude protein extracts from myocardial tissues of the left ventricle (LV) of the sham surgery group or of the LV area at risk (AAR), border zone (BZ), and remote area (RA) of the I/R group were used for proteasomal peptidase activity assays (A) and western blot analysis for ubiquitinated proteins (B, C). n=6 mice/group; *p<0.05, **p<0.01 vs. sham.