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. 2012 Jul 27;7:267–273. doi: 10.2147/CIA.S32836

Table 3.

Effect of BioCell Collagen ingestion on facial skin appearance

Measurement Week 0 (mean ± 1.00) Week 6 (mean ± SD) % change Week 12 (mean ± SD) % change % change



Wk 6-wk 0 P-value Wk 12-wk 0 P-value Wk 12-wk 6 P-value
Global lines/wrinkles 4.01 ± 1.00 4.91 ± 1.12 22.4 <0.001 3.48 ± 1.56 −13.2 0.028 −29.1 <0.001
Crow’s feet 2.88 ± 0.74 4.34 ± 0.95 50.7 <0.001 3.02 ± 1.28 4.9 0.422 −30.4 <0.001
Dryness/scaling 0.50 ± 0.51 0.38 ± 0.57 −24.0 0.416 0.12 ± 0.43 −76.0 0.002 −68.4 0.032

Abbreviation: SD, standard deviation.