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SCCHN cells express low basal pSTAT1 and high basal pSTAT3 that are inducible by treatment with IFN-γ and IL-6. Cells were treated with IFN-γ (100 U/ml, 15 min) or IL-6 (50 ng/ml, 15 min) and assayed for pSTAT1 (Tyrosine 701) or pSTAT3 (Tyrosine 705) by a intracellular flow cytometry or b immunoblot analyses. Data represent at least three independent experiments
