Fig. 3.

STAT1 signaling is intact in SCCHN cells. a SCCHN cells isolated from SCCHN tumors were tested for basal IFN-γR expression by flow cytometry. PCI-13 cells were treated with IFN-γ (100 U/ml) for either 15 min or 48 h and then analyzed by intracellular flow cytometry for either b pSTAT1 c or APM component expression, respectively. Data represent at least three independent experiments. Mean fluorescence intensity (MFI) was plotted, and error bars indicate standard error (*P < 0.005, *P < 0.001, two-tailed t test)