. Author manuscript; available in PMC: 2013 Jul 12.

Published in final edited form as: J Med Chem. 2012 Jun 22;55(13):6237–6241. doi: 10.1021/jm3005465

Table 1.

Dissociation equilibrium constants (K_d, nM) of ^DPMI-β, 6-F-Trp3-^DPMI-β, P-CF₃-Phe7-^DPMI-β, and ^DPMI-δ for synthetic ^(25-109)MDM2 and ^(24-108)MDMX.^[a]

	^DPMI-β	6-F-Trp3-^DPMI-β	p-CF₃-Phe7-^DPMI-β	^DPMI-δ
MDM2	37.8±0.9	14.0±1.0	0.45±0.41	0.22±0.21
MDMX	1440±41	1040±59	569±25	200±10

^[a]

Each K_d value (mean ± S.D.) was obtained from three independent measurements