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. Author manuscript; available in PMC: 2012 Aug 23.
Published in final edited form as: Pharm Res. 2011 Apr 7;28(8):1905–1918. doi: 10.1007/s11095-011-0418-5

Figure.10.

Figure.10

Comparison of intrinsic clearance (Vmax/Km) across UGT1A isoforms (UGT1A1,1A3 and 1A7~1A10) and four flavonols. Please also refer to Tab.2 & 3 for exact values. UGT1A1 and UGT1A9 were the most efficient conjugating enzymes with Vmax/Km of >3 ml/mg/min. Reference lines of 3 and 1.5 are shown.