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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Curr Drug Metab. 2011 Nov;12(9):900–916. doi: 10.2174/138920011797470100

Table 5.

Generalized regioselectivity of UGT1A1, 1A3, 1A9 or 1A10 towards four flavonoid subclasses: flavonols, flavones, flavanones, and isoflavones.

Backbone structure Supporting compounds
graphic file with name nihms394035t1.jpg Flavones graphic file with name nihms394035t2.jpg Chrysin [30,51] Flavones graphic file with name nihms394035t3.jpg 3,7-dihydroxyflavone [52,53]
6,7-dihydroxyflavone* Galangin [52]
Apigenin [51] Resokaempferol [52]
Baicalein [57] Kaempferol [52]
Wogonin [54] 3,3',4'-trihydroxyflavone*
Oroxylin A [54] Fisetin*
6,3’,4’-trihydroxyflavone* Quercetin*[56]
Luteolin* [55] Myricetin* [50]
Flavanone Hesperetin [33]
graphic file with name nihms394035t4.jpg Isoflavone graphic file with name nihms394035t5.jpg Daidzein [1,59]
Genistein [1,59]
Formononetin [1,59]
Biochanin A [1,59]
Prunetin [1,58,59]
Glycitein [1,59]
*

Please refer to Table 4 for kinetic parameters.