Representative micrographs show PAS-stained kidney sections from Control, CRF and CRF + F1-treated animals and quantitative data. A. Tubulointerstitial damage was undetectable in Control rats, prominent in CRF animals and significantly reduced in CRF + F1 rats. B. PAS staining of renal cortex showed significantly increased glomerulosclerosis in CRF rats compared to Control rats that was prevented with co-administration of F1. PAS: Periodic Acid Schiff. Magnification × 200, N=5-8, *p<0.001 vs. Control, **p<0.001 vs. CRF.