Table 3.
Parameters of lipid and glucose metabolism
Trait | SHR | SHR-mtLEW |
---|---|---|
Serum glucose, mmol/l | 3.8 ± 0.1 | 3.9 ± 0.1 |
AUC for glucose during OGTT, mmol·l−1·2 h−1 | 550 ± 19 | 545 ± 9 |
Serum NEFA at OGTT0 min, mmol/l | 1.93 ± 0.06 | 2.02 ± 0.08 |
Serum NEFA at OGTT60 min, mmol/l | 0.86 ± 0.08 | 1.10 ± 0.07* |
Serum NEFA, mmol/l | 0.48 ± 0.04 | 0.61 ± 0.03* |
Serum insulin, mmol/l | 0.76 ± 0.11 | 0.71 ± 0.04 |
Serum triglycerides, mmol/l | 2.1 ± 0.2 | 1.9 ± 0.2 |
Muscle triglycerides, μmol/g | 5.0 ± 0.7 | 5.0 ± 0.6 |
Values are means ± SE, n = 10 per strain,
P < 0.05. AUC, area under the curve; NEFA, nonesterified fatty acids; OGTT, oral glucose tolerance test.