Table 8.
Enriched syndrome genes
| 22q Like |
T21 Like |
Turner Like |
CHOP |
MFHS |
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Chr. | Gene | Gain, % | Loss, % | Gain, % | Loss, % | Gain, % | Loss, % | Gain, % | Loss, % | Gain, % | Loss, % | ||||||
| 1 | ACP6 | √ | 0.67 | 0.33 | 0.27 | 0.27 | √ | 0.42 | 0.42 | 0.05 | 0.05 | 0.00 | 0.23 | ||||
| 1 | BCL9 | √ | 0.67 | 0.33 | 0.27 | 0.27 | √ | 0.42 | 0.42 | 0.05 | 0.05 | 0.00 | 0.23 | ||||
| 1 | CHD1L | √ | 0.67 | 0.33 | 0.27 | 0.27 | √ | 0.84 | 0.42 | 0.05 | 0.05 | 0.00 | 0.23 | ||||
| 1 | FMO5 | √ | 0.67 | 0.33 | 0.27 | 0.27 | √ | 0.84 | 0.42 | 0.05 | 0.05 | 0.00 | 0.23 | ||||
| 1 | GJA5 | √ | 0.67 | 0.33 | 0.27 | 0.27 | √ | 0.42 | 0.42 | 0.05 | 0.05 | 0.00 | 0.23 | ||||
| 1 | PRKAB2 | √ | 0.67 | 0.33 | 0.27 | 0.27 | √ | 0.84 | 0.42 | 0.05 | 0.05 | 0.00 | 0.23 | ||||
| 6 | FOXC1 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | √ | 0.42 | 0.00 | 0.00 | 0.00 | 0.00 | |||||
| 8 | GATA4 | 0.00 | 0.33 | 0.00 | √ | 0.55 | √ | 0.42 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||
| 8 | SOX7 | 0.00 | 0.33 | 0.00 | √ | 0.55 | √ | 0.42 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||
| 9 | EHMT1 | 0.00 | 0.00 | 0.00 | 0.00 | √ | 0.42 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | |||||
| 9 | NOTCH1 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | √ | 0.42 | 0.00 | 0.00 | 0.00 | 0.00 | |||||
| 11 | HRAS | 0.00 | 0.00 | 0.27 | 0.00 | √ | 0.42 | 0.00 | 0.00 | 0.05 | 0.00 | 0.00 | |||||
| 18 | GATA6 | √ | 1.00 | 0.00 | √ | 0.55 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||
| 21 | RUNX1 | √ | 7.36 | 0.00 | √ | 22.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||
| 22 | CRKL | 0.67 | √ | 13.38 | 1.10 | √ | 3.57 | 0.00 | 0.00 | 0.00 | 0.05 | 0.34 | 0.00 | ||||
| 22 | TBX1 | 0.33 | √ | 14.05 | 0.55 | √ | 3.85 | 0.00 | 0.00 | 0.00 | 0.10 | 0.23 | 0.00 | ||||
| X | ATRX | 0.00 | 0.00 | 0.27 | 0.00 | 0.00 | √ | 8.99 | 0.00 | 0.00 | 0.00 | 0.00 | |||||
| X | BCOR | 0.00 | 0.00 | 0.27 | 0.00 | 0.00 | √ | 8.99 | 0.00 | 0.00 | 0.00 | 0.31 | |||||
| X | FLNA | 0.00 | 0.00 | 0.27 | 0.00 | 0.00 | √ | 8.99 | 0.10 | 0.00 | 0.00 | 0.00 | |||||
| X | GPC3 | 0.00 | 0.00 | 0.27 | 0.00 | 0.00 | √ | 8.99 | 0.00 | 0.00 | 0.00 | 0.00 | |||||
| X | MID1 | 0.00 | 0.00 | 0.27 | 0.00 | 0.00 | √ | 10.11 | 0.00 | 0.00 | 0.31 | 0.31 | |||||
| X | ZIC3 | 0.00 | 0.00 | 0.27 | 0.00 | 0.00 | √ | 8.99 | 0.10 | 0.00 | 0.00 | 0.00 | |||||
Boldface indicates significant values.