Fig. 3.

Cardiovascular and renal parameters in S and S.SHR(11) rats at week 12. Rats were raised on low salt (0.3% NaCl) until 6 wk of age and either continued on low-salt diet or were placed on high salt (2% NaCl) for 6 wk. A: blood urea nitrogen (BUN) and creatinine clearance (CrCl). B: mean arterial pressure (MAP). The average value is denoted above each graph. Parameters were determined using n = 14 per group, except for MAP, n = 8 per group. C: renal hemodynamic parameters: renal blood flow (RBF), glomerular filtration rate (GFR), and renal vascular resistance (RVR) in S and S.SHR(11) rats at week 12 on high salt. D: telemetry-measured blood pressure. For renal hemodynamic parameters, n = 6 (S) and n = 5 [S.SHR(11)]; n = 8 per group for telemetry. *P < 0.05 between groups. †P < 0.05 same strain different age/treatment.