Table 2.
Gene enrichment analyses of kidney protein spot abundance patterns
| k-Means Cluster | Functional Annotation Cluster | Cluster Enrichment | Annotations, n | Top Enrichment | Proteins, n |
|---|---|---|---|---|---|
| 1 | cytoplasmic membrane-bound vesicle | 3.8 | 4 | 14.5 | 5 |
| plasma | 2.0 | 9 | 82.7 | 4 | |
| 2 | mitochondrion | 6.4 | 6 | 29.8 | 17 |
| coenzyme binding | 5.0 | 3 | 23.9 | 6 | |
| lipoic acid binding | 3.1 | 3 | 309.1 | 3 | |
| generation of precursor metabolites and energy | 2.2 | 4 | 13.5 | 5 | |
| 3 | hexose metabolism | 6.8 | 3 | 22.9 | 8 |
| mitochondrion | 6.7 | 4 | 14.1 | 11 | |
| propanoate metabolism | 4.0 | 3 | 37.0 | 5 | |
| TCA cycle | 2.7 | 9 | 94.8 | 3 | |
| aldehyde dehydrogenase | 2.6 | 13 | 167.9 | 3 | |
| nicotinamide metabolism | 2.4 | 7 | 37.6 | 3 | |
| cell redox homeostasis | 1.3 | 4 | 47.4 | 3 | |
| 4 | mitochondrion | 3.1 | 4 | 13.6 | 6 |
| gluconeogenesis | 2.6 | 13 | 202.5 | 3 | |
| actin binding | 2.0 | 3 | 96.2 | 3 | |
| 5 | membrane-enclosed lumen | 7.9 | 3 | 3.8 | 23 |
| amino acid catabolism | 6.9 | 4 | 29.6 | 8 | |
| mitochondrial membrane | 6.0 | 8 | 15.9 | 12 | |
| TCA cycle | 3.2 | 7 | 3.2 | 4 | |
| aldehyde dehydrogenase | 2.8 | 16 | 101.4 | 4 | |
| electron transport | 2.5 | 3 | 38.5 | 4 | |
| nucleotide binding | 2.4 | 5 | 2.5 | 17 | |
| oxidative phosphorylation | 1.6 | 46 | 48.1 | 5 |