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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Mol Genet Metab. 2012 Jun 12;106(4):442–454. doi: 10.1016/j.ymgme.2012.05.025

Table 6.

O-linked glycans released from longitudinal samples of total plasma glycoprotein from infants with classic galactosemia. Patient number, gender, age at blood draw, GALT genotype, and gal-1P at blood draw are listed. None of these infants had detectable GALT activity in hemolysate.

Glycan structure Reference range from 40 controls Initial Follow-up Initial Follow-up Initial Follow-up
P2# ♂ P2 ♂ P2 ♂ P2 ♂ P3# ♀ P3 ♀ P7# ♀ P7 ♀
9 days (gal - 1P unk) 31 days (9.5 mg/dL) 59 days (5.3 mg/dL) 206 days (1.5 mg/dL) 8 days (15.7 mg/dL) 56 days (7.2 mg/dL) 13 days (52.4 mg/dL) 109 days (3.1 mg/dL)
graphic file with name nihms386677t23.jpg 0.22 μM -1.14 μM 0.2 0.37 0.31 0.50 0.62 0.47 0.33 0.36
graphic file with name nihms386677t24.jpg 11.7 μM -31.4 μM 1.9** 5.9** 7.1** 14.3 11.8 13.5 4.5** 43.1**
T/ST ≤0.06 0. 11** 0.06 0.03 0.05 0.05 0.07 0.07 0.01

Core1Tn-antigen (T), sialyl-T antigen (ST), and the ratio of T/ST are presented. Glycan symbols: □: N-acetylgalactosamine (GalNAc); ○: galactose; ◆: sialic acid (Neu5Ac). Shading and statistical significance are the same as for Table 1.