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Baseline to Week 12 endpoint changes in EORTC QLQ-C30 symptom scores. * For symptom scales, improvements are indicated by negative scores. ** p < 0.05 versus gp100 group. *** p > 0.05 for all comparisons (except for Constipation with p < 0.05). Mean change in scores were categorized as “no change” (0–5), “a little” (5–10 points), “moderate” (10–20 points), and “very much” (>20).
