Table 1. Cis-acting element consensus sequences changed by site-directed mutagenesis.
Gene | Sequence | |
NF-κB (2) (−1098/−1089) | Wild type | GGCGATTTCC |
Mutant | AATAGCCCTT | |
AP-1 (−820/−814) | Wild type | TGAAACA |
Mutant | CAGGTTG | |
NF-κB (1) (−336/−326) | Wild type | GGCGGCTTTCC |
Mutant | AATAATCCCTT | |
CREB (−138/−130) | Wild type | CCTACGTCA |
Mutant | TTCGTACTG |