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. 2012 Aug 23;8(8):e1002875. doi: 10.1371/journal.ppat.1002875

Figure 1. CRN8 domain composition and phylogenetic analysis of CRN8 paralogs.

Figure 1

(A) Cartoon of the three different motif combinations of CRN8 orthologs present in three sequenced Phytophthora genomes. The signal peptide (SP, black), LFLAK motif (blue), DWL motif (green), the NLS domain (red), and the kinase-homologous D2 domain (yellow) are presented as separate building blocks. The copy number of CRN8 paralogs and pseudogenes for three different sequenced Phytophthora genomes is stated alongside each CNR8 archetype. (B) Two phylogenetic trees of P. infestans (blue) and P. ramorum (orange) CRN8 paralogs based on amino acid sequence; the left side shows the N-terminus and the right side indicates the C-terminus. The originally identified CRN8 sequence from P. infestans isolate H88069 was also included (named CRN8). The other sequences are presented by their genome number. The N-terminal amino acid sequences in the left tree are connected by a dashed line to the C-terminal amino acid sequences of the right tree.