Figure 8.

Actin cytoskeleton restricts SERT mobility within membrane microdomains in a p38 MAPK and SERT C terminus-dependent manner. Plots of instantaneous velocity of A, single Qdot-labeled SERT proteins in RN46A cells treated with CytoD, B, single Qdot-labeled GM1/CTxB complexes in RN46A cells treated with CytoD, C, single Qdot-labeled SERT proteins in RN46A cells treated with CytoD after IL-1β stimulation, and D, single Qdot-labeled SERT proteins in RN46A cells treated with C-SERT peptide. Each condition represents results of three independent experiments.